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Methotrexate

Category

Anticancer Chemotherapy

Form

Injection

Strength

25mg/ml

CAS

59-05-2

Methotrexate Injection – Proven Anticancer & Immunosuppressive Therapy

Methotrexate Injection 25mg/ml is a well-established anticancer and immunosuppressive drug. Identified by CAS 59-05-2 with strong clinical validation. Works by inhibiting folic acid metabolism in rapidly dividing cells. Widely used in oncology and autoimmune treatments. Manufactured under WHO-GMP standards for global supply.

Used in leukemia, lymphoma, breast cancer, and osteosarcoma. Also used in autoimmune diseases like rheumatoid arthritis and psoriasis. Inhibits dihydrofolate reductase to block DNA synthesis. Widely used in combination chemotherapy regimens. Cost-effective and globally accepted therapy. Supported with COA, MSDS, and stability documentation.

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Important Information

  • Used in leukemia, lymphoma, breast cancer, and osteosarcoma.
  • Also used in autoimmune diseases like rheumatoid arthritis and psoriasis.
  • Inhibits dihydrofolate reductase to block DNA synthesis.
  • Widely used in combination chemotherapy regimens.
  • Cost-effective and globally accepted therapy.
  • Supported with COA, MSDS, and stability documentation.

Storage

  • Store at 20°C to 25°C
  • Protect from light and moisture
  • Keep in original packaging
  • Avoid freezing or excessive heat
  • Maintain controlled pharmaceutical storage conditions

Shelf Life

  • Typical shelf life: 24 to 36 months
  • Stability tested under global standards
  • Packaging prevents degradation
  • Clearly labeled expiry dates

Dosage

General

  • Dosage varies based on cancer type and severity
  • Used in combination chemotherapy protocols
  • Prescribed by healthcare professionals

Administration

  • Administered via intravenous, intramuscular, or intrathecal routes
  • Requires hospital or clinical setting
  • Handled by trained professionals

Important

  • Monitor liver function and blood counts
  • Ensure proper hydration
  • Strict adherence to dosing schedule

Manufacturing

  • Produced in WHO-GMP certified facilities
  • Advanced aseptic filling systems
  • ISO-compliant cleanroom environments
  • Rigorous sterility and stability testing
  • Compliance with USP, BP, and EP standards
  • Full regulatory documentation available

Precautions

  • Use only under medical supervision
  • Monitor liver and kidney function regularly
  • Avoid use during pregnancy and breastfeeding
  • Ensure adequate hydration
  • Avoid alcohol consumption

Side Effects

  • Nausea and vomiting
  • Bone marrow suppression
  • Mouth sores (mucositis)
  • Liver toxicity
  • Fatigue and weakness
  • Increased risk of infections

Expert View

  • One of the most versatile chemotherapy agents globally.
  • Widely used in both oncology and immunotherapy.
  • Cost-effective with strong clinical history.
  • Essential in combination cancer therapies.
  • Trusted worldwide for consistent outcomes.

Indications

  • Leukemia
  • Lymphoma
  • Breast cancer
  • Osteosarcoma
  • Rheumatoid arthritis
  • Psoriasis

Maintenance

  • Follow prescribed treatment schedule
  • Monitor liver and blood parameters regularly
  • Maintain hydration during therapy
  • Avoid missed doses
  • Continue under medical supervision

Why Choose

  • WHO-GMP certified manufacturing
  • Reliable global supply chain
  • Competitive bulk pricing
  • Complete regulatory documentation
  • Consistent product quality

Frequently Asked Questions

Common product and supply questions.

What is methotrexate injection used for?+

Methotrexate Injection is used to treat cancers such as leukemia, lymphoma, and breast cancer, and also to manage autoimmune diseases by slowing abnormal cell growth and immune activity.

What is the strongest chemotherapy for breast cancer?+

There is no single strongest chemotherapy, but Methotrexate Injection is widely used in combination therapies due to its effectiveness in slowing cancer cell growth.

Can methotrexate be used to fight cancer?+

Yes, Methotrexate Injection is a proven anticancer drug that inhibits DNA synthesis in cancer cells, making it effective in multiple oncology treatments.

Does methotrexate cause hair loss?+

Hair loss is less common compared to other chemotherapy drugs, but mild thinning may occur depending on dosage and duration.

What is the most serious side effect of methotrexate?+

The most serious side effects include liver toxicity and bone marrow suppression, requiring regular monitoring during treatment.