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Metformin Sustained Release

Category

Oral Antidiabetic

Form

Sustained Release Tablets

Strength

500mg / 1000mg

CAS

1115-70-4

Metformin Sustained Release Tablets – Extended Blood Glucose Control Therapy

Biguanide-class sustained-release formulation. Provides gradual and consistent glucose control. Available in 500mg and 1000mg strengths. Reduces gastrointestinal side effects. Manufactured under global pharmaceutical standards.

Metformin Sustained Release Tablets are widely used for long-term management of Type 2 diabetes. Identified by CAS Number 1115-70-4, it ensures pharmaceutical-grade quality. The sustained-release formulation allows gradual drug release, improving tolerability. It helps maintain stable blood glucose levels throughout the day. Manufactured under strict international pharmaceutical standards.

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Overview

  • Extended-release oral antidiabetic agent.
  • Reduces hepatic glucose production.
  • Improves insulin sensitivity.
  • Provides stable glycemic control.
  • Reliable sustained-release therapy.

Introduction

  • Metformin Sustained Release Tablets are widely used for long-term management of Type 2 diabetes.
  • Identified by CAS Number 1115-70-4, it ensures pharmaceutical-grade quality.
  • The sustained-release formulation allows gradual drug release, improving tolerability.
  • It helps maintain stable blood glucose levels throughout the day.
  • Manufactured under strict international pharmaceutical standards.

Important Information

  • Belongs to biguanide class.
  • CAS 1115-70-4 ensures traceability.
  • Available in 500mg and 1000mg strengths.
  • Sustained-release oral tablet formulation.
  • Requires medical supervision.

Dosage

General

  • Initial dose: 500mg once daily
  • Dose increased gradually based on tolerance
  • Maximum dose: up to 2000mg/day

Administration

  • Take with evening meal
  • Swallow whole; do not crush or chew
  • Maintain consistent dosing schedule
  • Do not skip doses

Important

  • Use under medical supervision
  • Monitor blood glucose regularly
  • Avoid overdose

Storage

  • Store below 25°C
  • Protect from moisture and heat
  • Keep in original packaging
  • Keep out of reach of children

Shelf Life

  • Typical shelf life: 24–36 months
  • Use before expiry date
  • Proper storage ensures stability

Manufacturing

  • Manufactured in WHO-GMP certified facilities
  • High-purity API (CAS 1115-70-4)
  • Advanced sustained-release matrix technology
  • Uniform drug release profile
  • Multi-stage quality testing
  • Global regulatory compliance

Precautions

  • Risk of lactic acidosis (rare)
  • Monitor kidney function regularly
  • Avoid excessive alcohol consumption
  • Use cautiously in elderly patients
  • Not suitable for severe renal impairment

Side Effects

  • Nausea
  • Diarrhea
  • Abdominal discomfort
  • Metallic taste
  • Loss of appetite
  • Rare vitamin B12 deficiency
  • Rare lactic acidosis

Expert View

  • Advanced sustained-release formulation.
  • Improves patient compliance.
  • Reduces gastrointestinal side effects.
  • Widely used globally.
  • Reliable long-term diabetes management.

Indications

  • Type 2 diabetes mellitus
  • Prediabetes management
  • Insulin resistance conditions
  • Combination therapy with other antidiabetics
  • Weight management in diabetic patients

Maintenance

  • Long-term therapy under supervision
  • Regular blood glucose monitoring
  • Lifestyle modifications essential
  • Dose adjustment as needed
  • Follow medical advice strictly

Why Choose

  • Sustained-release technology
  • Improved tolerability
  • WHO-GMP certified manufacturing
  • Reliable global supply
  • Consistent therapeutic performance

Frequently Asked Questions

Common product and supply questions.

What is the use of metformin sustained release tablets?+

Metformin sustained release tablets are used to manage Type 2 diabetes by providing extended blood sugar control throughout the day.

What is the difference between metformin and metformin sustained release?+

Metformin SR releases the drug slowly, offering longer action and fewer side effects compared to immediate-release forms.

What is the best medicine for prediabetes?+

Metformin is commonly used along with lifestyle changes for managing prediabetes.

Which is better, sustained release or prolonged release?+

Both provide controlled release, but sustained-release often improves tolerability and compliance.

What are the disadvantages of sustained release?+

They cannot be crushed and may have slower onset of action compared to immediate-release forms.

What is the advantage of using a sustained release tablet?+

It provides consistent drug levels, reduced dosing frequency, and improved patient compliance.