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Irinotecan Hydrochloride

Category

Anticancer

Form

Injection

Strength

20mg/ml

CAS

136572-09-3

Irinotecan Hydrochloride Injection 20mg/ml – Advanced Oncology Chemotherapy

Irinotecan Hydrochloride Injection 20mg/ml is a widely used anticancer chemotherapy medication. Identified by CAS 136572-09-3, it acts as a topoisomerase I inhibitor. Prevents DNA replication and promotes cancer cell death. Commonly used in colorectal cancer and solid tumor treatments. Manufactured under strict GMP standards ensuring global compliance.

Irinotecan Hydrochloride Injection is used in colorectal cancer treatment. Works by inhibiting DNA unwinding in cancer cells. Often combined with fluorouracil and leucovorin. Enhances effectiveness in combination chemotherapy regimens. Includes COA, MSDS, and stability documentation. Globally accepted oncology drug with strong clinical outcomes.

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Important Information

  • Irinotecan Hydrochloride Injection is used in colorectal cancer treatment.
  • Works by inhibiting DNA unwinding in cancer cells.
  • Often combined with fluorouracil and leucovorin.
  • Enhances effectiveness in combination chemotherapy regimens.
  • Includes COA, MSDS, and stability documentation.
  • Globally accepted oncology drug with strong clinical outcomes.

Storage

  • Store at 20°C to 25°C
  • Protect from light and moisture
  • Keep in original packaging
  • Avoid freezing or extreme temperatures
  • Maintain controlled pharmaceutical storage conditions

Shelf Life

  • Shelf life typically 24 to 36 months
  • Stability tested under international standards
  • Packaging prevents degradation
  • Expiry clearly labeled as per global guidelines

Dosage

General

  • Dosage determined by healthcare professional
  • Based on body surface area (BSA)
  • Depends on cancer type and treatment plan

Administration

  • Administered via intravenous infusion
  • Given in chemotherapy cycles
  • Requires strict medical supervision

Important

  • Regular blood count monitoring required
  • Hydration is essential during therapy
  • Proper dosing ensures safety and effectiveness

Manufacturing

  • Manufactured in WHO-GMP certified facilities
  • Advanced sterile production techniques
  • High-precision aseptic filling systems
  • ISO-compliant cleanroom environments
  • Rigorous quality control and validation
  • Complies with USP, BP, and EP standards
  • Full regulatory documentation available

Precautions

  • Use only under medical supervision
  • Monitor liver function and blood counts
  • Avoid during pregnancy unless prescribed
  • Ensure proper hydration
  • Dose adjustment required for elderly patients

Side Effects

  • Severe diarrhea
  • Nausea and vomiting
  • Bone marrow suppression
  • Hair loss (alopecia)
  • Fatigue and weakness
  • Increased infection risk

Expert View

  • Irinotecan is a cornerstone chemotherapy drug in colorectal cancer treatment.
  • Widely used in global oncology protocols.
  • Effective in combination therapies for improved outcomes.
  • Cost-effective and clinically proven solution.
  • Trusted by hospitals and oncology centers worldwide.

Indications

  • Colorectal cancer treatment
  • Solid tumor therapy
  • Combination chemotherapy regimens
  • Advanced oncology protocols

Maintenance

  • Follow prescribed chemotherapy cycles
  • Monitor blood counts and liver function
  • Maintain hydration and nutrition
  • Avoid missed doses during treatment
  • Continue under oncologist supervision

Why Choose

  • WHO-GMP certified production
  • Reliable global supply chain
  • Competitive bulk pricing
  • Complete regulatory documentation
  • Consistent high-quality manufacturing

Frequently Asked Questions

Common product and supply questions.

What is irinotecan hydrochloride injection used for?+

Irinotecan Hydrochloride Injection is used to treat colorectal cancer and other solid tumors by blocking DNA replication in cancer cells and preventing their growth.

Can irinotecan cure cancer?+

Irinotecan does not cure cancer but helps control disease progression and improve survival rates, especially when used in combination chemotherapy treatments.

What is the success rate of irinotecan injections?+

The success rate depends on cancer type and stage, but it has shown strong effectiveness in colorectal cancer when used in combination therapy.

What is the cost of irinotecan injection?+

The cost varies depending on dosage, manufacturer, and region. Bulk purchasing offers more competitive pricing for hospitals and distributors.

Is irinotecan injection safe?+

Irinotecan is safe under medical supervision but may cause side effects like diarrhea and low blood counts, requiring regular monitoring.

How much is 4 months of chemo?+

The cost of chemotherapy varies based on treatment cycles and healthcare facility, but institutional procurement usually offers better pricing.