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Gliclazide + Metformin Hydrochloride

Category

Oral Antidiabetic

Form

Tablets

Strength

80mg + 500mg

CAS

Combination

Gliclazide & Metformin Tablets – Dual-Action Blood Glucose Control

Combination of sulfonylurea and biguanide therapy. Enhances insulin secretion and sensitivity. 80mg + 500mg oral tablet formulation. Provides comprehensive glycemic control. Manufactured under global pharmaceutical standards.

Gliclazide & Metformin Tablets combine two effective mechanisms for managing Type 2 diabetes. Gliclazide stimulates pancreatic insulin secretion, while metformin reduces hepatic glucose production. This combination provides improved glycemic control compared to monotherapy. Widely used for patients not adequately controlled with a single drug. Manufactured under strict international pharmaceutical standards.

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Overview

  • Dual-action oral antidiabetic combination.
  • Stimulates insulin secretion and reduces glucose production.
  • Improves insulin sensitivity.
  • Effective for uncontrolled Type 2 diabetes.
  • Reliable combination therapy.

Introduction

  • Gliclazide & Metformin Tablets combine two effective mechanisms for managing Type 2 diabetes.
  • Gliclazide stimulates pancreatic insulin secretion, while metformin reduces hepatic glucose production.
  • This combination provides improved glycemic control compared to monotherapy.
  • Widely used for patients not adequately controlled with a single drug.
  • Manufactured under strict international pharmaceutical standards.

Important Information

  • Combination of gliclazide and metformin.
  • Available in 80mg + 500mg strength.
  • Oral tablet formulation.
  • Used for Type 2 diabetes management.
  • Requires medical supervision.

Dosage

General

  • Initial dose based on patient condition
  • Typically once or twice daily
  • Dose adjusted based on glycemic response

Administration

  • Take with meals
  • Swallow with water
  • Maintain consistent dosing schedule
  • Do not skip meals

Important

  • Use under medical supervision
  • Monitor blood glucose regularly
  • Avoid overdose

Storage

  • Store below 25°C
  • Protect from moisture and heat
  • Keep in original packaging
  • Keep out of reach of children

Shelf Life

  • Typical shelf life: 24–36 months
  • Use before expiry date
  • Proper storage ensures stability

Manufacturing

  • Manufactured in WHO-GMP certified facilities
  • High-purity APIs
  • Advanced combination formulation technology
  • Uniform drug distribution
  • Multi-stage quality testing
  • Global regulatory compliance

Precautions

  • Risk of hypoglycemia
  • Risk of lactic acidosis (rare)
  • Avoid alcohol consumption
  • Monitor kidney and liver function
  • Not suitable for Type 1 diabetes

Side Effects

  • Hypoglycemia
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort
  • Headache
  • Weight changes
  • Rare allergic reactions

Expert View

  • Effective dual-mechanism therapy.
  • Improves glycemic control significantly.
  • Widely used globally.
  • Requires careful monitoring.
  • Reliable diabetes management solution.

Indications

  • Type 2 diabetes mellitus
  • Patients uncontrolled by monotherapy
  • Combination therapy for better control
  • Long-term glycemic management

Maintenance

  • Long-term therapy under supervision
  • Regular blood glucose monitoring
  • Dose adjustments as needed
  • Lifestyle management essential
  • Follow medical advice strictly

Why Choose

  • Dual-action antidiabetic therapy
  • Improved glycemic control
  • WHO-GMP certified manufacturing
  • Reliable global supply
  • Consistent product quality

Frequently Asked Questions

Common product and supply questions.

What is gliclazide and metformin hydrochloride tablets used for?+

This combination is used to treat Type 2 diabetes by lowering blood sugar through improved insulin secretion and reduced glucose production.

What to avoid when taking gliclazide?+

Avoid alcohol, skipping meals, and excessive sugar intake as these can increase hypoglycemia risk.

Which tablet is best for sugar?+

The best treatment depends on individual conditions; combination therapies are often used for better control.

Why is gliclazide taken at night?+

It may be taken at night to maintain blood glucose levels overnight, depending on medical advice.

What are the bad side effects of gliclazide?+

Common side effects include hypoglycemia, nausea, dizziness, and rare allergic reactions.