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Gentamicin

Category

Antibacterial (Aminoglycoside)

Form

Injection

Strength

40mg/ml

CAS

1405-41-0

Gentamicin Injection – High-Potency Aminoglycoside for Critical Infections

Aminoglycoside antibacterial injection. Effective against gram-negative and select gram-positive bacteria. Available in 10ml and 30ml vial formats. Rapid bactericidal action for severe infections. Manufactured under international sterile standards.

Gentamicin Injection 40mg/ml is a widely used antibacterial formulation in critical care medicine. It belongs to the aminoglycoside class and works by inhibiting bacterial protein synthesis. Identified by CAS Number 1405-41-0, it is highly effective against serious infections. Commonly used in hospital settings for rapid bacterial control. Manufactured under strict pharmaceutical standards ensuring sterility and consistency.

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Overview

  • Aminoglycoside broad-spectrum antibacterial.
  • Inhibits bacterial protein synthesis.
  • Effective for severe and life-threatening infections.
  • Widely used in hospital and ICU settings.
  • Requires careful monitoring due to toxicity profile.

Introduction

  • Gentamicin Injection 40mg/ml is a widely used antibacterial formulation in critical care medicine.
  • It belongs to the aminoglycoside class and works by inhibiting bacterial protein synthesis.
  • Identified by CAS Number 1405-41-0, it is highly effective against serious infections.
  • Commonly used in hospital settings for rapid bacterial control.
  • Manufactured under strict pharmaceutical standards ensuring sterility and consistency.

Important Information

  • Belongs to aminoglycoside antibacterial class.
  • CAS 1405-41-0 ensures traceability.
  • Available as 40mg/ml injectable solution.
  • Available packs: 10ml and 30ml vials.
  • Requires strict medical supervision.

Dosage

General

  • Adults: 3–5 mg/kg/day divided into 2–3 doses
  • Severe infections: higher doses as prescribed
  • Pediatric & neonates: weight-based dosing
  • Duration: typically 5–10 days

Administration

  • Administer via IV or IM route
  • IV preferred for severe infections
  • Maintain sterile administration practices
  • Follow hospital protocols

Important

  • Use only under medical supervision
  • Adjust dose in renal impairment
  • Therapeutic drug monitoring recommended

Storage

  • Store below 25°C
  • Protect from light
  • Do not freeze
  • Keep vials tightly sealed

Shelf Life

  • Unopened vial: 24–36 months
  • Opened vial: use immediately or as per guidelines
  • Check expiry before use

Manufacturing

  • Manufactured in WHO-GMP certified facilities
  • High-purity API (CAS 1405-41-0)
  • Sterile liquid injectable production
  • Multi-stage filtration and sterilization
  • Strict quality control testing

Precautions

  • Use cautiously in renal impairment
  • Monitor kidney function regularly
  • Avoid prolonged use without supervision
  • Monitor hearing function during therapy
  • Use cautiously in elderly patients
  • Avoid in pregnancy unless necessary

Side Effects

  • Nephrotoxicity (kidney damage)
  • Ototoxicity (hearing loss)
  • Nausea
  • Vomiting
  • Dizziness
  • Injection site reactions
  • Allergic reactions
  • Rare neuromuscular blockade

Expert View

  • Highly effective for critical infections.
  • Essential antibiotic in ICU settings.
  • Requires strict monitoring due to toxicity.
  • Widely used in combination therapy.
  • Trusted in global hospital environments.

Indications

  • Septicemia (blood infections)
  • Respiratory tract infections
  • Urinary tract infections
  • Intra-abdominal infections
  • Bone and joint infections
  • Skin and soft tissue infections
  • Neonatal infections
  • Severe gram-negative infections

Maintenance

  • Typical treatment duration: 5–10 days
  • Monitor renal function
  • Adjust dose based on response
  • Use therapeutic drug monitoring
  • Complete full course under supervision

Why Choose

  • WHO-GMP certified manufacturing
  • High-potency antibacterial therapy
  • Reliable critical-care formulation
  • Export-quality standards
  • Consistent batch quality

Frequently Asked Questions

Common product and supply questions.

What is gentamicin injection used for?+

Gentamicin Injection is used to treat serious infections such as septicemia, respiratory infections, UTIs, and intra-abdominal infections.

How many days can one take gentamicin injection?+

Treatment typically lasts 5 to 10 days depending on infection severity and medical supervision.

Is gentamicin 80 mg IV or IM?+

Gentamicin can be administered both intravenously (IV) and intramuscularly (IM).

What is a Genticyn injection used for?+

Genticyn (gentamicin) is used to treat bacterial infections such as UTIs, respiratory infections, and septicemia.

What is a serious side effect of gentamicin?+

Serious side effects include kidney damage (nephrotoxicity) and hearing loss (ototoxicity).