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Cefepime

Category

Antibacterial (Cephalosporin)

Form

Injection (Vial)

Strength

500mg / 1g

CAS

88040-23-7

Cefepime Injection – Advanced Fourth-Generation Antibacterial Therapy

Fourth-generation cephalosporin antibacterial. Broad-spectrum activity against resistant bacteria. Stable against beta-lactamase enzymes. Ideal for hospital and ICU use. Manufactured under global sterile standards.

Cefepime Injection is a fourth-generation cephalosporin antibiotic used for serious bacterial infections. It works by disrupting bacterial cell wall synthesis, leading to bacterial elimination. Identified by CAS Number 88040-23-7, it ensures pharmaceutical-grade quality. Offers enhanced stability against beta-lactamase enzymes. Manufactured under strict international pharmaceutical standards.

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Overview

  • Fourth-generation cephalosporin antibiotic.
  • Inhibits bacterial cell wall synthesis.
  • Effective for severe and hospital-acquired infections.
  • Used in ICU and clinical settings.
  • Reliable injectable antibacterial therapy.

Introduction

  • Cefepime Injection is a fourth-generation cephalosporin antibiotic used for serious bacterial infections.
  • It works by disrupting bacterial cell wall synthesis, leading to bacterial elimination.
  • Identified by CAS Number 88040-23-7, it ensures pharmaceutical-grade quality.
  • Offers enhanced stability against beta-lactamase enzymes.
  • Manufactured under strict international pharmaceutical standards.

Important Information

  • Belongs to fourth-generation cephalosporin class.
  • CAS 88040-23-7 ensures traceability.
  • Available in 500mg and 1g strengths.
  • Injectable vial formulation.
  • Requires strict medical supervision.

Dosage

General

  • Adults: 1g every 12 hours or 2g every 8–12 hours
  • Severe infections: up to 2g every 8 hours
  • Children: weight-based dosing
  • Duration: typically 7–14 days

Administration

  • Administer via IV or IM route
  • Reconstitute with sterile water
  • Further dilute in IV fluids if required
  • Infuse over 30 minutes for IV use

Important

  • Use under medical supervision
  • Adjust dose in renal impairment
  • Complete full prescribed course

Storage

  • Store below 25°C
  • Protect from light
  • Keep in original packaging
  • Use reconstituted solution within recommended time

Shelf Life

  • Unopened vial: 24–36 months
  • After reconstitution: use immediately or as directed
  • Check expiry before use

Manufacturing

  • Manufactured in WHO-GMP certified facilities
  • High-purity API (CAS 88040-23-7)
  • Sterile powder filling technology
  • Advanced lyophilization process
  • Multi-stage quality assurance
  • Global regulatory compliance

Precautions

  • Adjust dose in renal impairment
  • Monitor neurological status in high doses
  • Avoid in cephalosporin allergy
  • Use cautiously in elderly patients
  • Monitor kidney function
  • Avoid unnecessary prolonged use

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Injection site reactions
  • Rash
  • Headache
  • Elevated liver enzymes
  • Rare seizures in renal impairment
  • Very rare hypersensitivity reactions

Expert View

  • Advanced hospital-grade antibacterial.
  • Highly effective against resistant organisms.
  • Preferred in ICU settings.
  • Broad-spectrum coverage.
  • Strong global clinical acceptance.

Indications

  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Intra-abdominal infections
  • Febrile neutropenia
  • Bacteremia
  • Post-surgical infections

Maintenance

  • Typical duration: 7–14 days
  • Continue based on clinical response
  • Adjust dose in renal impairment
  • Complete full course
  • Monitor patient response

Why Choose

  • Fourth-generation antibacterial therapy
  • Effective against resistant bacteria
  • WHO-GMP certified manufacturing
  • Reliable ICU-grade formulation
  • Global export-quality standards

Frequently Asked Questions

Common product and supply questions.

What is cefepime injection used for?+

Cefepime Injection is used to treat severe infections such as pneumonia, urinary tract infections, and bloodstream infections.

Is cefepime high risk?+

It is generally safe but may cause neurological side effects in high doses or kidney impairment.

How do you dilute cefepime?+

It is reconstituted with sterile water and diluted with IV fluids before administration.

Is cefepime stronger than ceftriaxone?+

Yes, it has broader Gram-negative coverage including resistant bacteria.

Is meropenem better than cefepime?+

Meropenem is used for highly resistant infections, while cefepime is effective for many severe infections.